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Innate response is intimately linked to acquired immunity. Chronic inflammation is an example of the innate immune system adapting to systemic changes, though the adaptation appears as disease, whereas it is in fact a symptom of a more systemic problem.
All multicellular eukaryotes have a complex innate immune system. The above description merely scratches the surface of the intricate interactions involved. This relatively primeval system is an astonishing collaboration of protection. But innate immunity is just the warm-up act.
